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[Cystic kidney disease and diabetes--an underdiagnosed monogenic developmental disorder].

Duodecim; laaketieteellinen aikakauskirja - 1 Jan 2012

Merenmies Jussi, Ala-Houhala Marja, Tuomi Tiinamaija

Abstract excerpt

Heterozygous mutations in the TCF2 gene encoding the transcription factor HNF-11 cause a dominantly inherited developmental disorder that may be associated with various dysplastic and cystic lesions of the kidneys and renal insufficiency, disorder of pancreatic development and insulin-deficient MODY diabetes, aberrant hepatic enzyme levels, gout and genital anomalies. Symptoms and findings vary in their degree of...

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PMID: 23155751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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