Article
Genetic dissection of peroxisome-associated matrix protein degradation in Arabidopsis thaliana.
Genetics - 1 Jan 2013
Burkhart Sarah E, Lingard Matthew J, Bartel Bonnie
Abstract excerpt
Peroxisomes are organelles that sequester certain metabolic pathways; many of these pathways generate H(2)O(2), which can damage proteins. However, little is known about how damaged or obsolete peroxisomal proteins are degraded. We exploit developmentally timed peroxisomal content remodeling in Arabidopsis thaliana to elucidate peroxisome-associated protein degradation. Isocitrate lyase (ICL) is a peroxisomal...
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