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Article

Synucleins: are they two-edged swords?

Journal of neuroscience research - 1 Feb 2013

Surguchov Andrei

Abstract excerpt

The synuclein family consists of three distinct highly homologous genes, α-synuclein, β-synuclein, and γ-synuclein, which have so far been found only in vertebrates. Proteins encoded by these genes are characterized by an acidic C-terminal region and five or six imperfect repeat motifs (KTKEGV) distributed throughout the highly conserved N-terminal region. Numerous data demonstrate that synucleins are implicated...

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PMID: 23150342
DOI: 10.1002/jnr.23149

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