Article
The effect of cone opsin mutations on retinal structure and the integrity of the photoreceptor mosaic.
Investigative ophthalmology & visual science - 5 Dec 2012
Carroll Joseph, Dubra Alfredo, Gardner Jessica C, Mizrahi-Meissonnier Liliana, Cooper Robert F, Dubis Adam M, Nordgren Rick, Genead Mohamed, Connor Thomas B, Stepien Kimberly E, Sharon Dror, Hunt David M, Banin Eyal, Hardcastle Alison J, Moore Anthony T, Williams David R, Fishman Gerald, Neitz Jay, Neitz Maureen, Michaelides Michel
Abstract excerpt
PURPOSE: To evaluate retinal structure and photoreceptor mosaic integrity in subjects with OPN1LW and OPN1MW mutations. METHODS: Eleven subjects were recruited, eight of whom have been previously described. Cone and rod density was measured using images of the photoreceptor mosaic obtained from an adaptive optics scanning light ophthalmoscope (AOSLO). Total retinal thickness, inner retinal thickness, and outer...
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