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Article

Determination of the full-genome sequence of hepatitis E virus (HEV) SAAS-FX17 and use as a reference to identify putative HEV genotype 4 virulence determinants.

Virology journal - 8 Nov 2012

Zhu Yumin, Yu Xiaoming, Huang Fenfen, Yu Ruisong, Dong Shijuan, Si Fusheng, Zhang Yuanshu, Li Zhen

Abstract excerpt

BACKGROUND: Four major genotypes of hepatitis E virus (HEV), the causative agent of hepatitis E, have so far been recognized. While genotypes 3 and 4 are both zoonotic, the disease symptoms caused by the latter tend to be more severe. To examine if specific nucleotide/amino acid variations between genotypes 3 and 4 play a role in determining the severity of hepatitis E disease, the complete genome of one swine...

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Identifiers

PMID: 23134633
DOI: 10.1186/1743-422X-9-264
PMCID: PMC3546022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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