Article
Virulent strain of hepatitis E virus genotype 3, Japan.
Emerging infectious diseases - 1 May 2009
Takahashi Kazuaki, Okamoto Hiroaki, Abe Natsumi, Kawakami Manri, Matsuda Hiroyuki, Mochida Satoshi, Sakugawa Hiroshi, Suginoshita Yoshiki, Watanabe Seishiro, Yamamoto Kazuhide, Miyakawa Yuzo, Mishiro Shunji
Abstract excerpt
Hepatitis E virus (HEV) genotype 3, which usually causes asymptomatic infection in Japan, induced severe hepatitis in 8 patients. To better understand genetic features of HEV associated with increased virulence, we determined the complete or near-complete nucleotide sequences of HEV from these 8 patients and from 5 swine infected with genotype 3 strain swJ19. Phylogenetic analysis showed that the isolates from...
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