Article
On the nature of mycobacteriophage diversity and host preference.
Virology - 20 Dec 2012
Jacobs-Sera Deborah, Marinelli Laura J, Bowman Charles, Broussard Gregory W, Guerrero Bustamante Carlos, Boyle Michelle M, Petrova Zaritza O, Dedrick Rebekah M, Pope Welkin H, Modlin Robert L, Hendrix Roger W, Hatfull Graham F
Abstract excerpt
The complete genome sequences of over 220 mycobacteriophages reveal them to be highly diverse, with numerous types sharing little or no nucleotide sequence identity with each other. We have determined the preferences of these phages for Mycobacterium tuberculosis and for other strains of Mycobacterium smegmatis, and find there is a correlation between genome type (cluster, subcluster, singleton) and host range....
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