Article
Telomere length is associated with ACE I/D polymorphism in hypertensive patients with left ventricular hypertrophy.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Sept 2013
Fyhrquist Frej, Eriksson Anders, Saijonmaa Outi, Nordestgaard Børge G, Kontula Kimmo, de Faire Ulf, Ibsen Hans, Kjeldsen Sverre, Os Ingrid, Dahlöf Björn
Abstract excerpt
INTRODUCTION: Short telomeres are often associated with cardiovascular risk factors and age-related diseases, while the angiotensin converting enzyme (ACE) gene insertion/deletion polymorphism (DD, ID, II) has shown such associations less consistently. We hypothesized that telomere length and association of telomere length with cardiovascular risk is affected by ACE (I/D) genotype. METHODS: We measured leucocyte...
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