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Article

From genotype to phenotype: can systems biology be used to predict Staphylococcus aureus virulence?

Nature reviews. Microbiology - 1 Nov 2012

Priest Nicholas K, Rudkin Justine K, Feil Edward J, van den Elsen Jean M H, Cheung Ambrose, Peacock Sharon J, Laabei Maisem, Lucks David A, Recker Mario, Massey Ruth C

Abstract excerpt

With the advent of high-throughput whole-genome sequencing, it is now possible to sequence a bacterial genome in a matter of hours. However, although the presence or absence of a particular gene can be determined, we do not yet have the tools to extract information about the true virulence potential of an organism from sequence data alone. Here, we focus on the important human pathogen Staphylococcus aureus and...

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Identifiers

PMID: 23070558
DOI: 10.1038/nrmicro2880
PMCID: PMC7097209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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