Article
Predicting the virulence of MRSA from its genome sequence.
Genome research - 1 May 2014
Laabei Maisem, Recker Mario, Rudkin Justine K, Aldeljawi Mona, Gulay Zeynep, Sloan Tim J, Williams Paul, Endres Jennifer L, Bayles Kenneth W, Fey Paul D, Yajjala Vijaya Kumar, Widhelm Todd, Hawkins Erica, Lewis Katie, Parfett Sara, Scowen Lucy, Peacock Sharon J, Holden Matthew, Wilson Daniel, Read Timothy D, van den Elsen Jean, Priest Nicholas K, Feil Edward J, Hurst Laurence D, Josefsson Elisabet, Massey Ruth C
Abstract excerpt
Microbial virulence is a complex and often multifactorial phenotype, intricately linked to a pathogen's evolutionary trajectory. Toxicity, the ability to destroy host cell membranes, and adhesion, the ability to adhere to human tissues, are the major virulence factors of many bacterial pathogens,...
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