The implications of genotype-environment correlation for establishing causal processes in psychopathology.

Abstract excerpt

The significance of genotype-environment interplay is its focus on how causal factors, whether environmental or genetic, have their effects. It is difficult to establish causality in observational research because of the potential for reverse causation and confounding. Most environmental measures are heritable, which means that their effects on the risk for psychopathology are potentially confounded by genotype....

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