Article
Molecular phenotyping of circulating tumour cells in patients with prostate cancer: prediction of distant metastases.
BJU international - 1 Dec 2012
Giesing Michael, Driesel Gerhard, Molitor Dietmar, Suchy Bernhard
Abstract excerpt
UNLABELLED: What's known on the subject? and What does the study add? The role of circulating cancer cells in metastogenesis is generally accepted. Two forms of these cells have been reported in a number of studies, cancer cell clusters (CCCs) and individual epithelial cancer cells. Clusters appear at higher frequencies in the blood. CCCs have been reported to be rich in vimentin and poor in E-cadherin expression...
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