Article
Reduced cell number in the hindgut epithelium disrupts hindgut left-right asymmetry in a mutant of pebble, encoding a RhoGEF, in Drosophila embryos.
Mechanisms of development - 1 Feb 2013
Nakamura Mitsutoshi, Matsumoto Kenjiroo, Iwamoto Yuta, Muguruma Takeshi, Nakazawa Naotaka, Hatori Ryo, Taniguchi Kiichiro, Maeda Reo, Matsuno Kenji
Abstract excerpt
Animals often show left-right (LR) asymmetry in their body structures. In some vertebrates, the mechanisms underlying LR symmetry breaking and the subsequent signals responsible for LR asymmetric development are well understood. However, in invertebrates, the molecular bases of these processes are largely unknown. Therefore, we have been studying the genetic pathway of LR asymmetric development in Drosophila. The...
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