Phylogenetic conservation of arylsulfatases. cDNA cloning and expression of human arylsulfatase B.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Phylogenetic conservation of arylsulfatases. cDNA cloning and expression of human arylsulfatase B.

The Journal of biological chemistry - 25 Feb 1990

Peters C, Schmidt B, Rommerskirch W, Rupp K, Zühlsdorf M, Vingron M, Meyer H E, Pohlmann R, von Figura K

Abstract excerpt

A 2.2-kilobase cDNA clone for human arylsulfatase B (ASB) and several genomic clones were isolated and sequenced. The deduced amino acid sequence of 533 amino acids contains a 41-amino acid N-terminal signal peptide and a mature polypeptide of 492 amino acid residues. Overexpression of ASB in transfected baby hamster kidney (BHK) cells resulted in up to 68-fold higher ASB activity than in untransfected BHK cells....

Topics

Amino Acid Sequence
Animals
Arylsulfatases
Base Sequence
Cell Line
Chondro-4-Sulfatase
Cloning, Molecular
DNA
Gene Expression
Genes
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Oligonucleotide Probes

Peptide Fragments

Phylogeny

Restriction Mapping

Sequence Homology, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 2303452

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2303452-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phylogenetic conservation of arylsulfatases. cDNA cloning and expression of human arylsulfatase B.PMID 2303452Read ↗

Structure of the human arylsulfatase B gene.Semantic proximity Read ↗

Hunter syndrome: isolation of an iduronate-2-sulfatase cDNA clone and analysis of patient DNA.Semantic proximity Read ↗

Murine arylsulfatase B: regulation of As-1 expression in different tissues.Semantic proximity Read ↗

Mucopolysaccharidosis VI (Maroteaux-Lamy syndrome): six unique arylsulfatase B gene alleles causing variable disease phenotypes.Semantic proximity Read ↗

Mucopolysaccharidosis type VI in rats: isolation of cDNAs encoding arylsulfatase B, chromosomal localization of the gene, and identification of the mutation.Semantic proximity Read ↗

Structure of the human laminin B2 chain gene reveals extensive divergence from the laminin B1 chain gene.Semantic proximity Read ↗

Analysis of the four alleles of the murine aryl hydrocarbon receptor.Semantic proximity Read ↗

Human Bleomycin Hydrolase: Molecular Cloning, Sequencing, Functional Expression, and Enzymatic CharacterizationSemantic proximity Read ↗

Characterization of four arylsulfatase A missense mutations G86D, Y201C, D255H, and E312D causing metachromatic leukodystrophy.Semantic proximity Read ↗

Characterization and Expression of the Human A2a Adenosine Receptor GeneSemantic proximity Read ↗

Cloning, expression and tissue distribution of the gene encoding rat fibroblast growth factor receptor subtype 4.Semantic proximity Read ↗

Secretoglobins: Sexually Dimorphic Expression of Androgen-Binding Protein mRNA in Mouse Lacrimal GlandsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.