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Article

Advanced complex trait analysis.

Bioinformatics (Oxford, England) - 1 Dec 2012

Gray A, Stewart I, Tenesa A

Abstract excerpt

MOTIVATION: The Genome-wide Complex Trait Analysis (GCTA) software package can quantify the contribution of genetic variation to phenotypic variation for complex traits. However, as those datasets of interest continue to increase in size, GCTA becomes increasingly computationally prohibitive. We present an adapted version, Advanced Complex Trait Analysis (ACTA), demonstrating dramatically improved performance....

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PMID: 23023980
DOI: 10.1093/bioinformatics/bts571

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