Article
DNA-based prenatal diagnosis of heritable skin diseases.
Archives of dermatology - 1 Nov 1993
Christiano A M, Uitto J
Abstract excerpt
BACKGROUND: Recent success in identifying candidate genes and demonstrating mutations in such genes has set the stage for DNA-based prenatal diagnosis of genodermatoses. An example of such conditions is epidermolysis bullosa in which discrete mutations have been identified in different forms of t...
Topics
- Alleles
- Blastomeres
- Chorionic Villi Sampling
- DNA
- Female
- Fetal Diseases
- Forecasting
- Genetic Carrier Screening
- Genetic Linkage
- Genetic Markers
- Genetic Therapy
- Genotype
- Humans
- Pedigree
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Pregnancy