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Article

Systematic identification of Lactobacillus plantarum auxotrophs for fermented Nham using genome-scale metabolic model.

Journal of biotechnology - 31 Dec 2012

Chiewchankaset Porntip, Srimarut Yanee, Klanchui Amornpan, Kurdi Peter, Plengvidhya Vethachai, Meechai Asawin

Abstract excerpt

In this study, a systematic strategy is presented, which identifies auxotrophic starters for the popular Thai fermented sausage product, called Nham, using a genome-scale metabolic model. A published genome-scale model of Lactobacillus plantarum WCFS1 is adopted for studying the L. plantarum BCC9546 characteristics cultured on Simulated Nham Broth. Single gene deletion analysis is performed to determine the genes...

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PMID: 23010606
DOI: 10.1016/j.jbiotec.2012.08.019

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