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Article

Pitfalls in the genetic diagnosis of Hb S.

Clinical biochemistry - 1 Mar 2013

Moradkhani Kamran, Riou Jean, Wajcman Henri

Abstract excerpt

Patients homozygous for Hb S need to be properly identified to start as early as possible a treatment that should avoid complications. For prevention and genetic counseling, carriers of Hb S have to be screened. Hb S is easily detected by several analytical systems, but other variants, usually harmless, may behave as Hb S, leading to false positive diagnosis. Some interactions may also cause difficulties in the...

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PMID: 22995479
DOI: 10.1016/j.clinbiochem.2012.08.018

Genes

SCD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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