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Article

A quantitative measure of handgrip myotonia in non-dystrophic myotonia.

Muscle & nerve - 1 Oct 2012

Statland Jeffrey M, Bundy Brian N, Wang Yunxia, Trivedi Jaya R, Raja Rayan Dipa, Herbelin Laura, Donlan Merideth, McLin Rhonda, Eichinger Katy J, Findlater Karen, Dewar Liz, Pandya Shree, Martens William B, Venance Shannon L, Matthews Emma, Amato Anthony A, Hanna Michael G, Griggs Robert C, Barohn Richard J

Abstract excerpt

INTRODUCTION: Non-dystrophic myotonia (NDM) is characterized by myotonia without muscle wasting. A standardized quantitative myotonia assessment (QMA) is important for clinical trials. METHODS: Myotonia was assessed in 91 individuals enrolled in a natural history study using a commercially available computerized handgrip myometer and automated software. Average peak force and 90% to 5% relaxation times were...

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Identifiers

PMID: 22987687
DOI: 10.1002/mus.23402
PMCID: PMC3564214

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