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Kaposi's sarcoma‐derived cell line SLK is not of endothelial origin, but is a contaminant from a known renal carcinoma cell line

17 Sept 2012

Abstract excerpt

Kaposi's sarcoma (KS) is an endothelial cell-derived tumor. Investigations of the molecular mechanisms of KS pathogenesis and the identification of drugs for treatment of KS depend critically on valid cell-culture models. Two major immortalized cell lines are available for KS research. Recently, the KS cell line KS Y-1 has been shown to be cross-contaminated with the T24 urinary bladder cancer cell line (ATCC...

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PMID: 22987579
DOI: 10.1002/ijc.27849

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