Article
No association between MTHFR C677T polymorphism and completed suicide.
Gene - 10 Dec 2012
Chojnicka Izabela, Sobczyk-Kopcioł Agnieszka, Fudalej Marcin, Fudalej Sylwia, Wojnar Marcin, Waśkiewicz Anna, Broda Grażyna, Strawa Katarzyna, Pawlak Aleksandra, Krajewski Paweł, Płoski Rafał
Abstract excerpt
MTHFR C677T polymorphism (rs1801133) was associated with numerous psychiatric conditions but no prior study investigated whether it predisposes to completed suicide. We typed rs1801133 in 692 suicide victims and 3257 controls representative of a Polish adult population (the WOBASZ cohort). Although we had a power of 0.8 to detect (at alpha 0.05) an allelic OR=1.19, we did not find significant difference among...
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