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Article

First WHO International Reference Panel containing hepatitis B virus genotypes A-G for assays of the viral DNA.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Dec 2012

Chudy M, Hanschmann K-M, Kress J, Nick S, Campos R, Wend U, Gerlich W, Nübling C M

Abstract excerpt

BACKGROUND: WHO International Standards (IS) are provided for the calibration and validation of diagnostic and screening assays, e.g. for hepatitis B virus (HBV). HBV forms numerous subgenotypes and the current IS for HBV DNA reflects subgenotype A2. OBJECTIVE: A reference panel with the most prevalent subgenotypes should facilitate evaluation of genotype-specific detection efficiencies. STUDY DESIGN: 215 HBV...

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Identifiers

PMID: 22981623
DOI: 10.1016/j.jcv.2012.08.013

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