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Genetic analysis of reaction time variability: room for improvement?

Psychological medicine - 1 Jun 2013

Kuntsi J, Frazier-Wood A C, Banaschewski T, Gill M, Miranda A, Oades R D, Roeyers H, Rothenberger A, Steinhausen H-C, van der Meere J J, Faraone S V, Asherson P, Rijsdijk F

Abstract excerpt

BACKGROUND: Increased reaction time variability (RTV) on cognitive tasks requiring a speeded response is characteristic of several psychiatric disorders. In attention deficit hyperactivity disorder (ADHD), the association with RTV is strong phenotypically and genetically, yet high RTV is not a stable impairment but shows ADHD-sensitive improvement under certain conditions, such as those with rewards. The state...

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Attention Deficit Disorder with Hyperactivity
Case-Control Studies
Inhibition, Psychological
Models, Genetic
Reaction Time

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Twins, Monozygotic

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PMID: 22975296
DOI: 10.1017/S0033291712002061
PMCID: PMC3801159

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