Article
Significance of genetic variation of PRRSV ORF5 in virus neutralization and molecular determinants corresponding to cross neutralization among PRRS viruses.
Veterinary microbiology - 22 Feb 2013
Kim Won-Il, Kim Jae-Jo, Cha Sang-Ho, Wu Wai-Hong, Cooper Vickie, Evans Rich, Choi En-Jin, Yoon Kyoung-Jin
Abstract excerpt
A high rate of genetic and antigenic variability among porcine reproductive and respiratory syndrome viruses (PRRSVs) hampers effective prevention and control of the disease caused by PRRSV. The major envelope protein (GP5) encoded by the ORF5 of PRRSV has a critical role in inducing virus neutra...
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