Article
Third trimester amniotic fluid cells with the capacity to develop neural phenotypes and with heterogeneity among sub-populations.
Restorative neurology and neuroscience - 1 Jan 2012
Bottai Daniele, Cigognini Daniela, Nicora Emanuela, Moro Monica, Grimoldi Maria Grazia, Adami Raffaella, Abrignani Sergio, Marconi Anna Maria, Di Giulio Anna Maria, Gorio Alfredo
Abstract excerpt
PURPOSE: Our aim was the search for new sources of cells potentially useful for central nervous system regenerative medicine. Extra-embryonic tissues are promising sources of pluripotent stem cells. Among these, human second-trimester amniotic fluid (AF) contains cell populations exhibiting self-renewal capacity, multipotency and the expression of embryonic cell markers. METHODS: Here we report the properties of...
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