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Establishment of a Reverse Genetics System for Studying Human Bocavirus in Human Airway Epithelia

30 Aug 2012

Abstract excerpt

Human bocavirus 1 (HBoV1) has been identified as one of the etiological agents of wheezing in young children with acute respiratory-tract infections. In this study, we have obtained the sequence of a full-length HBoV1 genome (including both termini) using viral DNA extracted from a nasopharyngeal aspirate of an infected patient, cloned the full-length HBoV1 genome, and demonstrated DNA replication, encapsidation...

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PMID: 22956907
DOI: 10.1371/journal.ppat.1002899

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