Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment.

doi:10.1073/pnas.1200072109

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Article

Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment.

Proceedings of the National Academy of Sciences of the United States of America - 18 Sept 2012

Coussens Anna K, Wilkinson Robert J, Hanifa Yasmeen, Nikolayevskyy Vladyslav, Elkington Paul T, Islam Kamrul, Timms Peter M, Venton Timothy R, Bothamley Graham H, Packe Geoffrey E, Darmalingam Mathina, Davidson Robert N, Milburn Heather J, Baker Lucy V, Barker Richard D, Mein Charles A, Bhaw-Rosun Leena, Nuamah Rosamond, Young Douglas B, Drobniewski Francis A, Griffiths Christopher J, Martineau Adrian R

Abstract excerpt

Calcidiol, the major circulating metabolite of vitamin D, supports induction of pleiotropic antimicrobial responses in vitro. Vitamin D supplementation elevates circulating calcidiol concentrations, and thus has a potential role in the prevention and treatment of infection. The immunomodulatory e...

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Identifiers

PMID: 22949664
DOI: 10.1073/pnas.1200072109
PMCID: PMC3458393

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22949664-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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