Article
Trophoblastic progranulin expression is upregulated in cases of fetal growth restriction and preeclampsia
13 May 2012
Abstract excerpt
AIMS: The expression of the anti-inflammatory glycoprotein progranulin and the hypoxia-induced transcription factor 1α (HIF-1α) in the villous trophoblast was compared between placentae from patients with preeclampsia (PE), fetal growth restriction (FGR), and normal controls. STUDY DESIGN: Matched pairs analysis of third trimester placentae specimens (mean gestational age 36+2) was performed by semiquantitative...
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