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Phage Display-based Strategies for Cloning and Optimization of Monoclonal Antibodies Directed against Human Pathogens

4 Jul 2012

Abstract excerpt

In the last two decades, several phage display-selected monoclonal antibodies (mAbs) have been described in the literature and a few of them have managed to reach the clinics. Among these, the anti-respiratory syncytial virus (RSV) Palivizumab, a phage-display optimized mAb, is the only marketed mAb directed against microbial pathogens. Palivizumab is a clear example of the importance of choosing the most...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22942702
DOI: 10.3390/ijms13078273

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