Development of Anti-Infectives Using Phage Display: Biological Agents against Bacteria, Viruses, and Parasites

Abstract excerpt

The vast majority of anti-infective therapeutics on the market or in development are small molecules; however, there is now a nascent pipeline of biological agents in development. Until recently, phage display technologies were used mainly to produce monoclonal antibodies (MAbs) targeted against cancer or inflammatory disease targets. Patent disputes impeded broad use of these methods and contributed to the...

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