Article
Molecular and phylogenetic analyses of human Parvovirus B19 isolated from Brazilian patients with sickle cell disease and β-thalassemia major and healthy blood donors.
Journal of medical virology - 1 Oct 2012
Slavov Svetoslav Nanev, Haddad Simone Kashima, Silva-Pinto Ana Cristina, Amarilla Alberto Anastacio, Alfonso Helda Liz, Aquino Victor Hugo, Covas Dimas Tadeu
Abstract excerpt
Human Parvovirus B19 (B19V) is a recognized cause of life-threatening conditions among patients with hemoglobinopathies. This study investigates B19V infection in patients with sickle cell disease and β-thalassemia using different experimental approaches. A total of 183 individuals (144 with sickle cell disease and 39 with β-thalassemia major) and 100 healthy blood donors were examined for B19V using anti-B19V...
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