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Human parvovirus B19: general considerations and impact on patients with sickle-cell disease and thalassemia and on blood transfusions

17 May 2011

Abstract excerpt

Human parvovirus B19 (B19V) is a small (22-24 nm) nonenveloped DNA virus belonging to the genus Erythrovirus (family Parvoviridae). Although it generally causes self-limiting conditions in healthy people, B19V infection may have a different outcome in patients with inherited hemolytic anemias. In such high-risk individuals, the high-titer replication may result in bone marrow suppression, triggering a...

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PMID: 21585562
DOI: 10.1111/j.1574-695x.2011.00819.x

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