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Article

Understanding and predicting complex traits: knowledge from cattle.

Human molecular genetics - 15 Oct 2012

Kemper Kathryn E, Goddard Mike E

Abstract excerpt

The genetic architecture of complex traits in cattle includes very large numbers of loci affecting any given trait. Most of these loci have small effects but occasionally there are loci with moderate-to-large effects segregating due to recent selection for the mutant allele. Genomic markers capture most but not all of the additive genetic variance for traits, probably because there are causal mutations with low...

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PMID: 22899652
DOI: 10.1093/hmg/dds332

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