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Article

Myotonic dystrophy: is a narrow focus obscuring the rest of the field?

Current opinion in neurology - 1 Oct 2012

Mahadevan Mani S

Abstract excerpt

PURPOSE OF REVIEW: The myotonic dystrophies (DM1 and DM2) are the paradigm for RNA toxicity in disease pathogenesis. The emphasis of this review will be on recent developments and issues in understanding the pathogenesis of DM1 and how this is driving the accelerated pace of translational and therapeutic developments. RECENT FINDINGS: RNA toxicity in myotonic dystrophy is now associated with bi-directional...

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Source

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Identifiers

PMID: 22892953
DOI: 10.1097/WCO.0b013e328357b0d9
PMCID: PMC4275308

Genes

MBNL1
DDX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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