Article
Schizophrenia shows a unique metabolomics signature in plasma.
Translational psychiatry - 14 Aug 2012
He Y, Yu Z, Giegling I, Xie L, Hartmann A M, Prehn C, Adamski J, Kahn R, Li Y, Illig T, Wang-Sattler R, Rujescu D
Abstract excerpt
Schizophrenia is a severe complex mental disorder affecting 0.5-1% of the world population. To date, diagnosis of the disease is mainly based on personal and thus subjective interviews. The underlying molecular mechanism of schizophrenia is poorly understood. Using targeted metabolomics we quantified and compared 103 metabolites in plasma samples from 216 healthy controls and 265 schizophrenic patients, including...
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