Article
Variants of the gentamicin and tobramycin resistance plasmid pRAY are widely distributed in Acinetobacter.
The Journal of antimicrobial chemotherapy - 1 Dec 2012
Hamidian Mohammad, Nigro Steven J, Hall Ruth M
Abstract excerpt
OBJECTIVES: To determine the cause of resistance to the aminoglycosides gentamicin and tobramycin in Acinetobacter isolates and the location of the resistance genes. METHODS: Australian Acinetobacter baumannii isolates were screened for resistance to aminoglycosides. PCR followed by restriction digestion of amplicons was used to detect genes and plasmids. Plasmids were isolated and examined by restriction...
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