Article
The utility of diagnostic biopsy specimens for predictive molecular testing in colorectal cancer.
Histopathology - 1 Dec 2012
Fadhil Wakkas, Ibrahem Salih, Seth Rashmi, AbuAli Ghada, Ragunath Krishna, Kaye Philip, Ilyas Mohammad
Abstract excerpt
AIMS: If stratified medicine is to be applied in the neoadjuvant setting, predictive testing will have to be undertaken on preoperative diagnostic biopsy specimens. The aim of this study was to evaluate whether a diagnostic biopsy was adequately representative of the main tumour in colorectal cancer. METHODS AND RESULTS: Thirty cases of paired biopsy and subsequent resection specimens were randomly selected....
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