Article
PhpA, a tyrosine phosphatase of Myxococcus xanthus, is involved in the production of exopolysaccharide.
Microbiology (Reading, England) - 1 Oct 2012
Mori Yumi, Maeda Miri, Takegawa Kaoru, Kimura Yoshio
Abstract excerpt
Protein-tyrosine phosphorylation plays a significant role in multiple cellular functions in bacteria. Bacterial tyrosine phosphatases catalyse the dephosphorylation of tyrosyl-phosphorylated proteins. Myxococcus xanthus PhpA shares homology with DNA polymerase and histidinol phosphatase family members. Recombinant His-tagged PhpA requires Mn(2+) or Co(2+) for phosphatase activity, and shows strict specificity for...
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