High-performance liquid chromatography of globin chains in the identification of human globin gene abnormalities.

doi:10.1016/0301-4622(90)88021-j

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Article

High-performance liquid chromatography of globin chains in the identification of human globin gene abnormalities.

Biophysical chemistry - 31 Aug 1990

Masala B, Manca L

Abstract excerpt

This article summarizes experience and data obtained using a previously developed reverse-phase high-performance liquid chromatography method (J.B. Shelton, J.R. Shelton and W.A. Schroeder, J. Liq. Chromatogr. 7 (1984) 1969) in the study of a number of hemoglobinopathies in the Sardinian populati...

Topics

Chromatography, High Pressure Liquid
Chromosome Deletion
Gene Rearrangement
Genes
Genetic Variation
Globins
Hemoglobin A
Humans
Infant, Newborn
Macromolecular Substances
Mutation
Reference Values

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