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Article

The Role of MicroRNA-146a in the Pathogenesis of the Diabetic Wound-Healing Impairment

31 Jul 2012

Abstract excerpt

The impairment in diabetic wound healing represents a significant clinical problem. Chronic inflammation is thought to play a central role in the pathogenesis of this impairment. We have previously shown that treatment of diabetic murine wounds with mesenchymal stem cells (MSCs) can improve healing, but the mechanisms are not completely defined. MicroRNA-146a (miR-146a) has been implicated in regulation of the...

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Share to Diabetic Foot Ulcer Assessment and Management
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PMID: 22851573
DOI: 10.2337/db12-0145

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