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Article

Non-targeted effects of photon and particle irradiation and the interaction with the immune system

1 Jan 2012

Abstract excerpt

Ionizing irradiation is an important clinical approach to treat solid tumors. Modern radiation technologies aim to selectively kill tumor cells and protect the surrounding normal tissue. The standard paradigm for radiation effects in cellular systems involves damage of the DNA including DNA double-strand breaks, which are considered as most effective in destroying tumor cells. Due to their enhanced physical and...

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Identifiers

PMID: 22837986
DOI: 10.3389/fonc.2012.00080

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