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Article

Overcoming drug resistance with alginate oligosaccharides able to potentiate the action of selected antibiotics.

Antimicrobial agents and chemotherapy - 1 Oct 2012

Khan Saira, Tøndervik Anne, Sletta Håvard, Klinkenberg Geir, Emanuel Charlotte, Onsøyen Edvar, Myrvold Rolf, Howe Robin A, Walsh Timothy R, Hill Katja E, Thomas David W

Abstract excerpt

The uncontrolled, often inappropriate use of antibiotics has resulted in the increasing prevalence of antibiotic-resistant pathogens, with major cost implications for both United States and European health care systems. We describe the utilization of a low-molecular-weight oligosaccharide nanomedicine (OligoG), based on the biopolymer alginate, which is able to perturb multidrug-resistant (MDR) bacteria by...

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Identifiers

PMID: 22825116
DOI: 10.1128/AAC.00525-12
PMCID: PMC3457396

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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