Article
A functional polymorphism in PER3 gene is associated with prognosis in hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver - 1 Oct 2012
Zhao Binyu, Lu Jianguo, Yin Jikai, Liu Hanqiang, Guo Xu, Yang Yefa, Ge Naijian, Zhu Yong, Zhang Hongxin, Xing Jinliang
Abstract excerpt
BACKGROUND: Previous studies have revealed that circadian genes play important roles in cell proliferation, apoptosis, cell cycle control, DNA damage response and treatment response of chemotherapy agents in cancers. AIMS: We hypothesized that the polymorphisms in circadian genes may be associated with prognosis of hepatocellular carcinoma (HCC) patients treated with transcatheter arterial chemoembolization...
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