Article
High risk for essential hypertension in males conferred by g.15241A>G polymorphism in intron 3 of AGT gene.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2013
Padma Gunda, Bhupatiraju Charita, Srinivas Bhyravavajhala, Padma Tirunilai
Abstract excerpt
A total of 180 hypertensive and 188 normotensive subjects were studied for demographic features and for variations in exon 4 including exon-intron boundary of AGT gene using single-strand conformation polymorphism analysis. Sequencing of the samples showing mobility shift revealed a single-nucleotide polymorphism variant g.15241A>G in intron 3 of the gene. The polymorphism was consistent with Hardy-Weinberg...
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