Article
Interaction of the dopaminergic and serotonergic systems significantly influences the risk for multisomatoform disorder: a controlled pilot study.
Genetic testing and molecular biomarkers - 1 Aug 2012
Pahl Lisa, Bernateck Michael, Jakobi Jana, Tran Anh-Thu, Volkmann Lilly, Buers Dennis, Lehmann Ulrich, Karst Matthias, Stuhrmann Manfred
Abstract excerpt
The etiology of multisomatoform disorder (MSD) is largely unknown, but an influence of genetic factors is likely. Since pain is a major component of MSD and dopamine as well as serotonin are involved in pain pathways, genes of the dopaminergic and serotonergic system are promising candidate genes and we assumed that polymorphisms could be associated with MSD. One hundred forty-nine patients with MSD and 149 age-...
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