Article
[Determination of hematopoietic clonality by detection of multiple X-linked gene exonic polymorphic loci using transcription-based clonality assays].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Apr 2012
Liu Liu, Ma Xiao-tang, Wang Jie-yu, Su Tao, Yang Lin, Xu Ze-feng, Qin Tie-jun, Xiao Zhi-jian
Abstract excerpt
OBJECTIVE: To explore the frequencies of heterozygosity in X-linked G6PD, P55, BTK, and FHL-1 gene exonic polymorphic loci among Chinese females and the value of determination of hematopoietic clonality by detection of these X-chromosome exonic polymorphisms based on X-chromosome inactivation patterns (XCIP)-transcription-based clonality assays (TCA). METHODS: Genomic DNA was extracted from peripheral blood of...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Asian People
- Chromosomes, Human, X
- Exons
- Female
- Genes, X-Linked
- Genetic Carrier Screening
- Genetic Linkage
- Glucosephosphate Dehydrogenase