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Article

What we know and would like to know about CDKL5 and its involvement in epileptic encephalopathy.

Neural plasticity - 1 Jan 2012

Kilstrup-Nielsen Charlotte, Rusconi Laura, La Montanara Paolo, Ciceri Dalila, Bergo Anna, Bedogni Francesco, Landsberger Nicoletta

Abstract excerpt

In the last few years, the X-linked serine/threonine kinase cyclin-dependent kinase-like 5 (CDKL5) has been associated with early-onset epileptic encephalopathies characterized by the manifestation of intractable epilepsy within the first weeks of life, severe developmental delay, profound hypotonia, and often the presence of some Rett-syndrome-like features. The association of CDKL5 with neurodevelopmental...

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Source

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Identifiers

PMID: 22779007
DOI: 10.1155/2012/728267
PMCID: PMC3385648

Genes

CDKL5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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