Article
Development of an allele-specific, loop-mediated, isothermal amplification method (AS-LAMP) to detect the L1014F kdr-w mutation in Anopheles gambiae s. l.
Malaria journal - 6 Jul 2012
Badolo Athanase, Okado Kyioshi, Guelbeogo Wamdaogo M, Aonuma Hiroka, Bando Hironori, Fukumoto Shinya, Sagnon N'Fale, Kanuka Hirotaka
Abstract excerpt
BACKGROUND: Malaria control relies heavily on treated bed nets and indoor residual spraying with pyrethroid insecticides. Unfortunately, the resistance to pyrethroid insecticides, mainly due to the kdr mutation, is spreading in the main malaria vector Anopheles gambiae s.l., decreasing the insecticides' efficacy. To manage the insecticide resistance rapidly and flexibly, simple and effective tools for the early...
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