Article
Deficits in probabilistic classification learning and liability for schizophrenia.
Psychiatry research - 30 Dec 2012
Wagshal Dana, Knowlton Barbara Jean, Cohen Jessica Rachel, Poldrack Russell Alan, Bookheimer Susan Yost, Bilder Robert Martin, Fernandez Vindia Gisela, Asarnow Robert Franklin
Abstract excerpt
Patients with schizophrenia show deficits in skill learning. We tested the hypothesis that impaired skill learning is associated with liability for schizophrenia by determining if it is present in non-affected siblings of patients. This study examined cognitive skill learning in adolescent siblings of patients with childhood onset schizophrenia (COS), who are at high genetic risk for the disorder, and age-matched...
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