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Article

Histone H2B monoubiquitination is required to reach maximal transcript levels of circadian clock genes in Arabidopsis.

The Plant journal : for cell and molecular biology - 1 Oct 2012

Himanen Kristiina, Woloszynska Magdalena, Boccardi Tommaso M, De Groeve Steven, Nelissen Hilde, Bruno Leonardo, Vuylsteke Marnik, Van Lijsebettens Mieke

Abstract excerpt

Previously, we identified HISTONE MONOUBIQUITINATION1 (HUB1) as an unconventional ubiquitin E3 ligase that is not involved in protein degradation but in the histone H2B modification that is implicated in transcriptional activation in plants. HUB1-mediated regulation of gene expression played a role in periodic and inducible processes such as the cell cycle, dormancy, flowering time and defense responses. Here, we...

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PMID: 22762858
DOI: 10.1111/j.1365-313X.2012.05071.x

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